{"id":33958,"date":"2026-06-30T17:22:07","date_gmt":"2026-06-30T21:22:07","guid":{"rendered":"https:\/\/ncseagrant.ncsu.edu\/coastwatch\/?p=33958"},"modified":"2026-07-06T16:01:19","modified_gmt":"2026-07-06T20:01:19","slug":"can-gene-editing-serve-the-blue-economy","status":"publish","type":"post","link":"https:\/\/ncseagrant.ncsu.edu\/coastwatch\/can-gene-editing-serve-the-blue-economy\/","title":{"rendered":"Can Gene-Editing Serve the Blue Economy?"},"content":{"rendered":"\n\n\n\n\n
.<\/p>\n\n\n\n Molecular mechanisms could help coral reefs survive a warming ocean.<\/p>\n <\/div>\n<\/blockquote>\n\n\n\n On a healthy reef, color dominates. It feels like living in a kaleidoscope \u2013 vivid oranges, electric blues, and branching corals teeming with life. But across the Caribbean, that vividness is fading. Today\u2019s divers see an environment that looks like a gravel parking lot scattered with a few lonely coral heads. <\/p>\n\n\n\n \u201cIf you were to dive on any given coral reef in the Caribbean,\u201d says Jake Warner, an assistant professor of marine biology at the University of North Carolina Wilmington, \u201cyou would see a few solitary coral heads and a lot of dead coral rubble.\u201d<\/p>\n\n\n\n Research shows that up to 99% of warm-water coral reefs could disappear by 2050<\/a><\/strong>, with climate change driving the losses. Warmer oceans trigger coral bleaching, a process in which heat-stressed corals expel the photosynthetic algae living in their tissues, which provide the majority of their nutrition. Bleached corals may not die immediately, but they become vulnerable to disease, mortality, and habitat loss while threatening biodiversity and human coastal livelihoods. <\/p>\n\n\n\n \u201cA dead reef is not good for anyone,\u201d says Scott Baker Jr., fisheries specialist with North Carolina Sea Grant. \u201cNot for tourism, diving, and certainly not good for the fish and invertebrates that rely on healthy corals as part of their life cycle.\u201d<\/p>\n\n\n\n Healthy reefs are the backbone of a blue economy, supporting about 25% of all marine life and driving billions of dollars in tourism, fisheries, and shoreline protection for coastal states like North Carolina. <\/p>\n\n\n\n One disease in particular, Stony Coral Tissue Loss Disease, has spread through the Florida Keys<\/strong><\/a> in recent years. \u201cEverything is happening at once,\u201d Warner explains. \u201cTemperature, disease, pollution — they\u2019re all interacting.\u201d <\/p>\n\n\n\n UNCW Center for Marine Science is at the forefront of coral engineering. While most conservation efforts focus on preserving reefs or gardening corals by replanting them, Warner\u2019s approach is to study the animals\u2019 molecular makeup to understand and potentially improve their resilience. <\/p>\n\n\n\n \u201cPreservation is probably the least likely to happen just based on human nature,\u201d Warner says. \u201cCoral gardening is extremely labor-intensive and a stopgap. If you\u2019re not fixing the underlying problem of the environment, it\u2019s a Sisyphean task.\u201d<\/p>\n\n\n\n Corals are quite difficult research subjects. Most tropical species reproduce once or twice in a year<\/a><\/strong>, usually in the middle of the night following a late summer full moon. \u201cIn the past, you had to be out on a reef with nets in the dark, often in remote locations without a lab nearby,\u201d Warner explains. <\/p>\n\n\n\n To address this, the UNCW team built the Spawning and Embryo Analysis System, a series of tanks fitted with lights that mimic seasonal sunlight and moonlight as well as water temperature controls that track Caribbean seasons. <\/p>\n\n\n\n Corals kept inside these tanks spawn on schedule, releasing their gametes — reproductive cells — into the water there in the lab. \u201cRather than going to the field with all our equipment, we can actually bring the field to us,\u201d Warner says.\u00a0<\/p>\n\n\n\n While corals are often associated with tropical reefs, North Carolina is home to Astrangia poculata, <\/em>commonly known as the northern star coral. Found along the East Coast, from Florida to Massachusetts, it is a temperate coral that Warner uses as a primary subject in his lab. <\/p>\n\n\n\n He describes it as \u201cvery low maintenance,\u201d because Astrangia poculata <\/em>can survive a wide range of temperatures, offering a unique way to understand how corals adapt to environmental stress. Its ability to survive year-round in lab conditions makes it valuable for experiments that are difficult with tropical species. <\/p>\n\n\n\n Warner\u2019s lab collects the eggs and uses CRISPR-Cas9, a gene-editing technology like “molecular scissors” that cut DNA at precise locations. These techniques are still in their early stages in coral gene editing.\u00a0<\/p>\n\n\n\n \u201cWe\u2019re still at the stage of asking basic questions,\u201d he says. \u201cWhat makes a coral a coral?\u201d<\/p>\n\n\n\n Past experiments have already shown that disabling certain heat-response genes makes corals less able to survive high temperatures. Other studies have identified genes essential for skeleton formation. Warner\u2019s team focuses on this kind of foundational work. <\/p>\n\n\n\n His lab performs gene knockouts — genetic engineering techniques that delete a specific gene in an organism to make it non-functional — in order to silence a gene called coadhesin<\/a><\/strong><\/em>. Without it, coral larvae are unable to form their calcium carbonate skeletons. <\/p>\n\n\n\n Despite its promise, most of this work remains experimental. Scientists are still building the knowledge needed before large-scale applications, such as reef restoration, can be feasible. One of the main challenges to this promise is scalability.<\/p>\n\n\n\n \u201cCoral gene editing is still very low throughput, it\u2019s very expensive, and it would be a tiny drop in an enormous ocean,\u201d Warner says.<\/p>\n\n\n However, from a fisheries perspective, that long shot is worth taking. <\/p>\n\n\n\n \u201cHealthy habitat is the building block of healthy fisheries, and I don\u2019t feel we should dismiss any opportunity to improve habitat, even if that approach is different,\u201d says Baker. \u201cYou can\u2019t know if it works if you don\u2019t try.\u201d<\/p>\n\n\n\n The idea of releasing genetically modified corals into the ocean also raises complex ethical and geopolitical questions. Coral larvae can drift for miles on ocean currents and for weeks before settling, crossing national boundaries and potentially colonizing another country\u2019s reef. <\/p>\n\n\n\n \u201cThere\u2019s no geopolitical border in the sea,\u201d says Warner. \u201cWhat you do in one country could easily end up in another.\u201d<\/p>\n\n\n\n For now, the work remains in the lab, studying embryos, tracking gene activity, refining tools, and building knowledge needed to understand coral biology. But as oceans continue to warm, the question is no longer whether reefs are changing but whether science can keep up.<\/p>\n\n\n\n more on healthy ecosystems<\/strong><\/a><\/p>\n\n\n\n lead photo credit: adobestock.<\/em><\/p>\n\n\n\n Emma Davies<\/strong> is an award-winning journalist and a contributing editor for Coastwatch<\/em>. Her work includes the \u201cAcross the Atlantic\u201d series<\/a><\/strong>. She recently completed her master\u2019s in liberal studies at NC State University, with a concentration in communication and genetic engineering.<\/p>\n\n\n\n <\/p>\n\n\n
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<\/a>\n \u201cHealthy habitat is the building block of healthy fisheries,” says Baker, “and I don\u2019t feel we should dismiss any opportunity to improve habitat.”\n <\/blockquote>\n\n\n\n